Biochemists Lourdes and Liliana work at a laboratory. One day, they steal a drug that has high levels of female hormones and give it to their oblivious husbands to force each of them to experience a day in the life of a woman.
A police commander fails to take down a dangerous drug cartel, despite using all the limited equipment at his disposal, and his best detectives as undercover agents.
Some incidents occur on the dancing floor, and the ladies' restroom at a tropical club will change the life of a macho politician, a naive and subdued married woman, an unfaithful lesbian couple, a transsexual dreaming of a sex reassignment surgery and a smart school teacher who loses her head after a few drinks.
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